Tutorials

In this tutorial, you will learn:

  • how to draw your structure in the sketcher.
  • how to represent the attachment point of your structure with an R group (R1).

In this tutorial, you will learn:

  • how to navigate in the output of a side chain fragment query (cf Tutorial #1)
  • how to sort your results according to specific columns
  • how to filter your results according to ΔlogP and ΔtPSA of the candidate fragments
  • how to copy-paste or print your results as well as export them in CSV, XLS and PDF formats
  • how to dive into further analyses for a specific candidate among all outputted fragment

In this tutorial, you will learn:

  • how to navigate in the output of a side chain fragment query (cf Tutorial #6)
  • how to sort your results according to specific columns
  • how to filter your results according to compound A activity, assay type, confidence and result type
  • how to copy-paste or print your results as well as export them in CSV, XLS and PDF formats
  • how to get detailed information on compounds, assays and publications regarding a given replacement occurrence

In this tutorial, you will learn:

  • how to draw your structure in the sketcher
  • how to represent the attachment points of your structure with an R group:
    • Side chain: 1 R group (R1)
    • Linker: 2 R groups (R1, R2)
    • Scaffold: 3 R groups (R1, R2, R3)
  • how to check all attachment point contexts of replacement occurrences

In this tutorial, you will learn:

  • how to look for all occurrences of a specific replacement directly from the input page

In this tutorial, you will learn how to send a compound present in an occurrence of your replacement:

  • to SwissSimilary; to perform ligand-based virtual screening
  • to SwissTargetPrediction; to predict macromolecular targets
  • to SwissADME; to estimate the pharmacokinetics, druglikeness and medicinal chemistry friendliness
  • back to SwissBioisostere; to search for replacements of a molecular fragment

In this tutorial, you will learn:

  • how to send a compound to SwissBioisostere from the output of another SwissDrugDesign tool
  • how to look for additional information concerning your results
  • how to access SwissBioisostere FAQ and contact form